BDBM50041973 CHEMBL3358937
SMILES CC(C)(CC(O)(Cc1cc2cc(ncc2[nH]1)N1CCOCC1)C(F)(F)F)c1ccccc1S(C)(=O)=O
InChI Key InChIKey=VDSMZEJGVOMCGQ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50041973
Affinity DataIC50: 2nMAssay Description:Agonist activity at GR in HFF cells assessed as suppression of IL-1-induced IL-6 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-benzyloxy-4-(trifluoromethyl)-coumarin as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of RU-486 from GR (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of RU-486 from MR (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of tetramethylrhodamine-labeled dexamethasone from PR (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human ERG channel expressed in recombinant HEK293 cells by whole cell patch-clamp techniqueMore data for this Ligand-Target Pair