BDBM50042205 1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione::CHEMBL287129

SMILES CCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccccc1

InChI Key InChIKey=CLFCOXMMCBVJJB-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50042205   

TargetAdenosine receptor A2b(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  19nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  150nMAssay Description:Inhibition of [3H]CCPA binding to rat adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  150nMAssay Description:Binding affinity at A1 adenosine receptor in rat brain cortical membrane using [3H]- N6-R-phenylisopropyladenosine (R-PIA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  950nMAssay Description:Inhibition of [3H]PSB-11 binding to human Adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Pharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity against Adenosine A2 receptor in rat striatal membranes using [3H]5'-(N-ethylcarboxamido)-adenosine (NECA) as the ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of [3H]MSX-2 binding to rat adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed