BDBM50042206 1-Allyl-3,7-dihydro-purine-2,6-dione::CHEMBL66899

SMILES C=CCn1c(=O)[nH]c2nc[nH]c2c1=O

InChI Key InChIKey=IPKIKTHDWDXHPU-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50042206   

TargetAdenosine receptor A2b(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042206(1-Allyl-3,7-dihydro-purine-2,6-dione | CHEMBL66899)
Affinity DataKi:  461nMAssay Description:Binding affinity at human Adenosine A2B receptor expressed in HEK293 cells, using [125I]ABOPX as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Pharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50042206(1-Allyl-3,7-dihydro-purine-2,6-dione | CHEMBL66899)
Affinity DataKi:  9.20E+3nMAssay Description:Binding affinity at A1 adenosine receptor in rat brain cortical membrane using [3H]- N6-R-phenylisopropyladenosine (R-PIA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Pharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50042206(1-Allyl-3,7-dihydro-purine-2,6-dione | CHEMBL66899)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity against Adenosine A2 receptor in rat striatal membranes using [3H]5'-(N-ethylcarboxamido)-adenosine (NECA) as the ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042206(1-Allyl-3,7-dihydro-purine-2,6-dione | CHEMBL66899)
Affinity DataKi:  1.61E+4nMAssay Description:Inhibition of [125I]I-AB-MECA binding to human Adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Pharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50042206(1-Allyl-3,7-dihydro-purine-2,6-dione | CHEMBL66899)
Affinity DataKi:  2.43E+4nMAssay Description:Binding affinity of specific [3H]R-PIA binding to rat Adenosine A1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed