BDBM50042531 5-Butyl-2-(2,3-dichloro-phenyl)-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2H-pyrazole-3-carboxylic acid ethyl ester::CHEMBL419321

SMILES CCCCc1nn(c(C(=O)OCC)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=YKLQGVQJYASHPG-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50042531   

TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042531(5-Butyl-2-(2,3-dichloro-phenyl)-4-[2'-(1H-tetrazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of metallo-beta-lactamase (MBL) from Bacteroides fragilis.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042531(5-Butyl-2-(2,3-dichloro-phenyl)-4-[2'-(1H-tetrazol...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of metallo-beta-lactamase (MBL) from Pseudomonas aeruginosa mediated by the plasmid-borne IMP-1 enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042531(5-Butyl-2-(2,3-dichloro-phenyl)-4-[2'-(1H-tetrazol...)
Affinity DataIC50: 90nMAssay Description:Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidase 1(Pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50042531(5-Butyl-2-(2,3-dichloro-phenyl)-4-[2'-(1H-tetrazol...)
Affinity DataKi:  1.70E+5nMAssay Description:In vitro apparent inhibition constant of porcine renal Dehydropeptidase-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed