BDBM50042610 CHEMBL332202::Sodium; 7-[4-(4-fluoro-3,5-dimethyl-phenyl)-5-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate

SMILES Cc1cc(cc(C)c1F)-c1nc(n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=BNJTUCRVQVPSJG-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042610   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042610(Sodium; 7-[4-(4-fluoro-3,5-dimethyl-phenyl)-5-(4-f...)
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against washed rat liver microsomal HMG-CoA reductase (HMGR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed