BDBM50042620 (E)-(3R,5S)-7-[5-(4-Fluoro-phenyl)-2-isopropyl-4-(3-methanesulfonyl-phenyl)-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL331899::Sodium; 7-[5-(4-fluoro-phenyl)-2-isopropyl-4-(3-methanesulfonyl-phenyl)-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate

SMILES CC(C)c1nc(c(-c2ccc(F)cc2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=VCWDRTWXFLVEDT-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042620   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042620((E)-(3R,5S)-7-[5-(4-Fluoro-phenyl)-2-isopropyl-4-(...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against washed rat liver microsomal HMG-CoA reductase (HMGR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50042620((E)-(3R,5S)-7-[5-(4-Fluoro-phenyl)-2-isopropyl-4-(...)
Affinity DataIC50: 8.70nMAssay Description:Inhibitory concentration against 3-hydroxy-3-methylglutaryl-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed