BDBM50042628 (E)-(3R,5S)-7-[4,5-Bis-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL333307::Sodium; 7-[4,5-bis-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate

SMILES O[C@H](C[C@H](O)\C=C\n1c(nc(c1-c1ccc(F)cc1)-c1ccc(F)cc1)C(F)(F)F)CC([O-])=O

InChI Key InChIKey=WQXDCZIGRVCRLY-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042628   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042628((E)-(3R,5S)-7-[4,5-Bis-(4-fluoro-phenyl)-2-trifluo...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against washed rat liver microsomal HMG-CoA reductase (HMGR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50042628((E)-(3R,5S)-7-[4,5-Bis-(4-fluoro-phenyl)-2-trifluo...)
Affinity DataIC50: 7.89nMAssay Description:Inhibitory concentration against 3-hydroxy-3-methylglutaryl-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed