BDBM50044003 CHEMBL3356430

SMILES COCCOCC1(CCN(CC1)c1ncnc2[nH]cc(C)c12)C(=O)Nc1cccc(OC(=O)N(C)C)c1

InChI Key InChIKey=PNEHHQFPYPNPDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044003   

TargetRho-associated protein kinase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044003(CHEMBL3356430)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human Rock1 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044003(CHEMBL3356430)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed