BDBM50044168 CHEMBL3313995

SMILES Cc1c(cc(-c2cc(cc(c2)C(C)(C)C)C(C)(C)C)n1CC1CCCCC1)S(N)(=O)=O

InChI Key InChIKey=MDNCTLPREGRJBQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044168   

TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044168(CHEMBL3313995)
Affinity DataEC50: <500nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044168(CHEMBL3313995)
Affinity DataEC50: <500nMAssay Description:Agonist activity at RoRc-LBD (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed