BDBM50044228 CHEMBL3218920

SMILES CCC(=O)Nc1ccc2nn(nc2c1)-c1ccc(CC)cc1

InChI Key InChIKey=XZHWCIAHPTUIPY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044228   

TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044228(CHEMBL3218920)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human RoRc-LBD expressed in Jurkat cells assessed as IL-17 reporter activity by luciferase assay in absence of anti-CD3More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044228(CHEMBL3218920)
Affinity DataEC50:  100nMAssay Description:Agonist activity at RORgammat in human Jurkat cells ssessed as increase in IL17A production incubated for overnight by luciferase reporter gene AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2020
Entry Details Article
PubMed