BDBM50044255 CHEMBL3314016

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(Cl)c2)-c2ccccc2OC(F)(F)F)cc1

InChI Key InChIKey=CBYGRUDVWLATGL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044255   

TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044255(CHEMBL3314016)
Affinity DataEC50:  1nMAssay Description:Activity at human RoRc in human Jurkat cells assessed as inhibition of IL-17 promoterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044255(CHEMBL3314016)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of RORgammat (unknown origin) assessed as inhibition of agonist-induced response by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed