BDBM50044280 CHEMBL3356896

SMILES COc1cncc(c1)-c1ccc2nc(NC(=O)NCCC(=O)NCC(F)(F)F)sc2c1

InChI Key InChIKey=IIZVKFYZFQTGEB-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044280   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Vertex Pharmaceuticals

Curated by ChEMBL

LigandBDBM50044280(CHEMBL3356896)Copy SMILESCopy InChI

Affinity DataKi:  1nMAssay Description:Inhibition of PI3K-gamma (unknown origin) using [33P]ATP as substrate after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/20/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Vertex Pharmaceuticals

Curated by ChEMBL

LigandBDBM50044280(CHEMBL3356896)Copy SMILESCopy InChI

Affinity DataKi:  72nMAssay Description:Inhibition of PI3K-alpha (unknown origin) using [33P]ATP as substrate after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/20/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL