BDBM50044344 2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::2-Benzyl-5-butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL422593

SMILES CCCCc1nn(Cc2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=CLIGTAMVAYBTCT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50044344   

TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044344(2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 4.60nMAssay Description:In vitro antagonistic activity for angiotensin II receptor, type 1 by displacing 125I[Sar, ILe8 ]AII radioligand in rabbit aorta membrane without usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor B(Rat)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044344(2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [125I]angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044344(2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 4.60nMAssay Description:In vitro antagonistic activity for angiotensin II receptor, type 1 by displacing 125I[Sar, ILe8 ]AII radioligand in rabbit aorta membrane without usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50044344(2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]-angiotensin 2 from angiotensin AT1 receptor in Rattus norvegicus (rat) uterine membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

LigandPNGBDBM50044344(2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]-angiotensin 2 from angiotensin AT1 receptor in Rattus norvegicus (rat) uterine membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044344(2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity at angiotensin 2 type-1 receptor in Oryctolagus cuniculus (rabbit) aorta in presence of bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044344(2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity at angiotensin 2 type-1 receptor in Oryctolagus cuniculus (rabbit) aorta in presence of bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article