BDBM50044427 1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10,12,14-hexaen-4-yl isothiocyanate::CHEMBL312471

SMILES C[C@]12N[C@H](Cc3ccc(cc13)N=C=S)c1ccccc21

InChI Key InChIKey=IROZIFSXGAXYRY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50044427   

TargetSigma non-opioid intracellular receptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi:  4.82E+3nMAssay Description:Tested for in vitro inhibition of the displacement of (+)-[3H]pentazocine from sigma opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi:  6.95E+3nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]mazindol from GABA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]quinuclidinyl benzilate muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]FOXY from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed