BDBM50044514 5-Butyl-2-(1-phenyl-ethyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL85545

SMILES CCCCc1nn(C(C)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=VDBADUIMECELIQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50044514   

TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044514(5-Butyl-2-(1-phenyl-ethyl)-4-[2'-(2H-tetrazol-5-yl...)
Affinity DataIC50: 4.90nMAssay Description:In vitro antagonistic activity for angiotensin II receptor, type 1 by displacing 125I[Sar, ILe8 ]AII radioligand in rabbit aorta membrane without usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044514(5-Butyl-2-(1-phenyl-ethyl)-4-[2'-(2H-tetrazol-5-yl...)
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at angiotensin 2 type-1 receptor in Oryctolagus cuniculus (rabbit) aorta in presence of bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044514(5-Butyl-2-(1-phenyl-ethyl)-4-[2'-(2H-tetrazol-5-yl...)
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at angiotensin 2 type-1 receptor in Oryctolagus cuniculus (rabbit) aorta in presence of bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article