BDBM50044783 CHEMBL3309549

SMILES C[C@H](O)CNc1nccc(n1)-n1ccnc1Cc1cccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c1

InChI Key InChIKey=QKYKUTTWIHRLFI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50044783   

TargetSerine/threonine-protein kinase B-raf(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50044783(CHEMBL3309549)
Affinity DataIC50: 38nMAssay Description:Inhibition of BRAF V599E mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50044783(CHEMBL3309549)
Affinity DataIC50: 186nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50044783(CHEMBL3309549)
Affinity DataIC50: 571nMAssay Description:Inhibition of P38a/MAPK14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50044783(CHEMBL3309549)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of cRAF1 (unknown origin) at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed