BDBM50044833 CHEMBL3311184

SMILES CCCNc1cc(NC(=O)c2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=CSKJIIXTWHNKSV-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044833   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50044833(CHEMBL3311184)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293-TREx cells assessed as change in calcium level by Fluo-4NW assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetCytochrome P450 1A2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50044833(CHEMBL3311184)Copy SMILESCopy InChI

Affinity DataIC50: 140nMAssay Description:Competitive inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL