BDBM50044877 8-Fluoro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one::CHEMBL131803

SMILES CN1[C@H]2CCc3cc(F)ccc3[C@H]2CCC1=O

InChI Key InChIKey=YPMSVDVECSNPIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044877   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50044877(8-Fluoro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benz...)
Affinity DataIC50: 320nMAssay Description:In vitro inhibition of DHT production in Hs 68 (human genital fibroblast) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50044877(8-Fluoro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benz...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibitory concentration required to inhibit Steroid 5-alpha-reductase type 1 in cultured Hs 68 human foreskin fibroblast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article