BDBM50044885 (4aS,10bR)-8-Chloro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one::8-Chloro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one::CHEMBL281204

SMILES CN1[C@H]2CCc3cc(Cl)ccc3[C@H]2CCC1=O

InChI Key InChIKey=WQBIOEFDDDEARX-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50044885   

LigandPNGBDBM50044885(8-Chloro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benz...)
Affinity DataKi:  15nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

LigandPNGBDBM50044885(8-Chloro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benz...)
Affinity DataKi:  15nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

LigandPNGBDBM50044885(8-Chloro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benz...)
Affinity DataIC50: 41nMAssay Description:In vitro inhibition of DHT production in Hs 68 (human genital fibroblast) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50044885(8-Chloro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benz...)
Affinity DataKi:  1.00E+3nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

LigandPNGBDBM50044885(8-Chloro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benz...)
Affinity DataKi:  5.40E+3nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article