BDBM50044950 CHEMBL3309308

SMILES FC(F)(F)S(=O)(=O)c1cc(ccc1N[C@H](CCN1CCOCC1)CSc1ccccc1)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2cccnc2-c2ccc(Cl)cc2)CC1

InChI Key InChIKey=YJBUMWXBEUBVLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044950   

TargetApoptosis regulator Bcl-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50044950(CHEMBL3309308)
Affinity DataIC50: 26nMAssay Description:Inhibition of c-terminal 6xHis-tagged Bcl-2 (amino acids 1 to 204) (unknown origin) preincubated for 1 hr prior to substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50044950(CHEMBL3309308)
Affinity DataIC50: 25nMAssay Description:Inhibition of c-terminal 6xHis-tagged Bcl-xL (amino acids 1 to 209) (unknown origin) preincubated for 1 hr prior to substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed