BDBM50044955 CHEMBL3309402

SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(F)cc5)c(=O)c5ccccc45)cc3F)ccnc2cc1OCCCN1CCCC1

InChI Key InChIKey=MWXLURJNASFGGM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50044955   

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50044955(CHEMBL3309402)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of c-Met (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50044955(CHEMBL3309402)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of c-KIT (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50044955(CHEMBL3309402)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of FLT3 (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50044955(CHEMBL3309402)
Affinity DataIC50: 16nMAssay Description:Inhibition of PDGFRalpha (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50044955(CHEMBL3309402)
Affinity DataIC50: 70nMAssay Description:Inhibition of VEGFR2 (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50044955(CHEMBL3309402)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed