BDBM50044977 CHEMBL3334621

SMILES CC(C)(C#N)c1ccc(cc1)N1C(=O)OCc2cnc3ccc(cc3c12)-c1cnc2ccccc2c1

InChI Key InChIKey=DPLMXAYKJZOTKO-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50044977   

TargetSerine-protein kinase ATM(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 36nMAssay Description:Inhibition of ATM (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 36nMAssay Description:Inhibition of DNAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 14nMAssay Description:Inhibition of ATR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 545nMAssay Description:Inhibition of flag tagged- ATM (unknown origin) expressed in Escherichia coli BL21 incubated for 20 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 14nMAssay Description:Inhibition of flag tagged- ATR (unknown origin) expressed in Escherichia coli BL21 incubated for 20 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 36nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 170nMAssay Description:Inhibition of PIK3alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed