BDBM50045360 (20RS)-1N-(7-ethyl-7-hydroxy-8,11-dioxo-7,8,11,13-tetrahydro-10H-[1,3]dioxolo[5,4-g]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-15-yl)-2-aminoacetamide; hydrochloride::CHEMBL540569

SMILES CCC1(O)C(=O)OCc2c1cc1-c3nc4cc5OCOc5c(NC(=O)CN)c4cc3Cn1c2=O

InChI Key InChIKey=DDKBTHCWKLNKSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50045360   

TargetDNA topoisomerase 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045360((20RS)-1N-(7-ethyl-7-hydroxy-8,11-dioxo-7,8,11,13-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in intact human HL-60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045360((20RS)-1N-(7-ethyl-7-hydroxy-8,11-dioxo-7,8,11,13-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in intact human HL-60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed