BDBM50045386 (20RS)-4-(2-Bromo-ethyl)-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione::CHEMBL91495

SMILES OC1(CCBr)C(=O)OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O

InChI Key InChIKey=MAQYQWZDOMEUJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045386   

TargetDNA topoisomerase 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045386((20RS)-4-(2-Bromo-ethyl)-4-hydroxy-1,12-dihydro-4H...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in intact human HL-60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed