BDBM50045558 CHEMBL3314274

SMILES CCOP(=O)(CCn1cc(nn1)-c1ccn2c(c(nc2n1)-c1ccc(F)cc1)-c1ccnc(SC)n1)OCC

InChI Key InChIKey=FBUBDEOFMHAIPS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50045558   

TargetMitogen-activated protein kinase 14(Human)
Syncom

Curated by ChEMBL
LigandPNGBDBM50045558(CHEMBL3314274)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Syncom

Curated by ChEMBL
LigandPNGBDBM50045558(CHEMBL3314274)
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of CK1-delta (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Syncom

Curated by ChEMBL
LigandPNGBDBM50045558(CHEMBL3314274)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of JAK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Syncom

Curated by ChEMBL
LigandPNGBDBM50045558(CHEMBL3314274)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of JAK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Syncom

Curated by ChEMBL
LigandPNGBDBM50045558(CHEMBL3314274)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of JAK3 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed