BDBM50045614 2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL1204306::CHEMBL320684

SMILES OCCN1CCN(CC1)C1CC(c2cc(F)ccc12)c1ccc(F)cc1

InChI Key InChIKey=XISRGFHXAPVIRZ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50045614   

TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045614(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045614(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045614(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50045614(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 72nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenoceptors in whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50045614(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 72nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenoceptors in whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50045614(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenoceptors in whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045614(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 330nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045614(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 330nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045614(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed