BDBM50045616 1-(2-{4-[3-(4-Fluoro-phenyl)-5-methylsulfanyl-indan-1-yl]-piperazin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL92408

SMILES CSc1ccc2C(CC(c2c1)c1ccc(F)cc1)N1CCN(CCN2CCN(C(C)C)C2=O)CC1

InChI Key InChIKey=AYQDRJYOATYGDZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50045616   

TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045616(1-(2-{4-[3-(4-Fluoro-phenyl)-5-methylsulfanyl-inda...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50045616(1-(2-{4-[3-(4-Fluoro-phenyl)-5-methylsulfanyl-inda...)
Affinity DataIC50: 250nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenoceptors in whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045616(1-(2-{4-[3-(4-Fluoro-phenyl)-5-methylsulfanyl-inda...)
Affinity DataIC50: 720nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed