BDBM50045618 1-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-pyrrolidin-2-one dihydrochloride::CHEMBL2447982

SMILES Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCC3=O)CC2)c2ccc(Cl)cc12

InChI Key InChIKey=YWYGXPHDDJVFRM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50045618   

TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045618(1-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50045618(1-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50: 370nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenoceptors in whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045618(1-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50: 500nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed