BDBM50045656 2,2-Dimethyl-3-[4-methyl-6-(5-phenyl-pyridin-2-ylmethoxy)-1-pyridin-2-ylmethyl-4,5-dihydro-1H-3-thia-1-aza-acenaphthylen-2-yl]-propionic acid::CHEMBL96300

SMILES CC1Cc2c(OCc3ccc(cn3)-c3ccccc3)ccc3n(Cc4ccccn4)c(CC(C)(C)C(O)=O)c(S1)c23

InChI Key InChIKey=DJOHEBROURTEMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50045656   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50045656(2,2-Dimethyl-3-[4-methyl-6-(5-phenyl-pyridin-2-ylm...)
Affinity DataIC50: 45nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50045656(2,2-Dimethyl-3-[4-methyl-6-(5-phenyl-pyridin-2-ylm...)
Affinity DataIC50: 110nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed