BDBM50045669 3-[1-(3-Methoxy-benzyl)-4-methyl-6-(5-phenyl-pyridin-2-ylmethoxy)-4,5-dihydro-1H-3-thia-1-aza-acenaphthylen-2-yl]-2,2-dimethyl-propionic acid::CHEMBL96767

SMILES COc1cccc(Cn2c(CC(C)(C)C(O)=O)c3SC(C)Cc4c(OCc5ccc(cn5)-c5ccccc5)ccc2c34)c1

InChI Key InChIKey=RBBJYTRZLITXEF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50045669   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50045669(3-[1-(3-Methoxy-benzyl)-4-methyl-6-(5-phenyl-pyrid...)
Affinity DataIC50: 28nMAssay Description:Tested for inhibition of 5-HPETE production by human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50045669(3-[1-(3-Methoxy-benzyl)-4-methyl-6-(5-phenyl-pyrid...)
Affinity DataIC50: 40nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed