BDBM50045688 5-{1-[1-(1-Cyclohexylmethyl-2,3-dihydroxy-5-pyridin-2-yl-pentylcarbamoyl)-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethylcarbamoyl}-pentanoic acid ethyl ester::CHEMBL329818

SMILES CCOC(=O)CCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CCc1ccccn1

InChI Key InChIKey=OBDCVYACZSZHHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50045688   

TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50045688(5-{1-[1-(1-Cyclohexylmethyl-2,3-dihydroxy-5-pyridi...)
Affinity DataIC50: 0.690nMAssay Description:Selectivity against sheep plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50045688(5-{1-[1-(1-Cyclohexylmethyl-2,3-dihydroxy-5-pyridi...)
Affinity DataIC50: 0.75nMAssay Description:In vitro inhibition of renin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed