BDBM50045757 3-[3,4-Dimethyl-1-(tetrahydro-furan-2-ylmethyl)-piperidin-4-yl]-phenol::CHEMBL98403

SMILES C[C@H]1CN(CC2CCCO2)CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=YTCFSEQUWGPVLS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50045757   

TargetKappa-type opioid receptor(Guinea pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045757(3-[3,4-Dimethyl-1-(tetrahydro-furan-2-ylmethyl)-pi...)
Affinity DataKi:  9.30nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]EKC at 10 nM from guinea pig cortical tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045757(3-[3,4-Dimethyl-1-(tetrahydro-furan-2-ylmethyl)-pi...)
Affinity DataKi:  26nMAssay Description:Binding affinity towards mu-opioid receptor by displacement of [3H]NAL at 10 nM from rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045757(3-[3,4-Dimethyl-1-(tetrahydro-furan-2-ylmethyl)-pi...)
Affinity DataKi:  29nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]EKC at 100 nM from guinea pig cortical tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045757(3-[3,4-Dimethyl-1-(tetrahydro-furan-2-ylmethyl)-pi...)
Affinity DataKi:  60nMAssay Description:Binding affinity towards mu-opioid receptor by displacement of [3H]NAL at 100 nM from rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed