BDBM50045759 3-[3,4-Dimethyl-1-(4-thiophen-2-yl-butyl)-piperidin-4-yl]-phenol::CHEMBL264797

SMILES C[C@H]1CN(CCCCc2cccs2)CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=PXERKRHOUYBZAC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50045759   

TargetKappa-type opioid receptor(Guinea pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045759(3-[3,4-Dimethyl-1-(4-thiophen-2-yl-butyl)-piperidi...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]EKC at 10 nM from guinea pig cortical tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045759(3-[3,4-Dimethyl-1-(4-thiophen-2-yl-butyl)-piperidi...)
Affinity DataKi:  23nMAssay Description:Binding affinity towards mu-opioid receptor by displacement of [3H]NAL at 10 nM from rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045759(3-[3,4-Dimethyl-1-(4-thiophen-2-yl-butyl)-piperidi...)
Affinity DataKi:  69nMAssay Description:Binding affinity towards mu-opioid receptor by displacement of [3H]NAL at 100 nM from rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045759(3-[3,4-Dimethyl-1-(4-thiophen-2-yl-butyl)-piperidi...)
Affinity DataKi:  72nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]EKC at 100 nM from guinea pig cortical tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed