BDBM50045864 2-[2-(4-Chloro-phenyl)-1-methyl-1H-indol-3-yl]-N,N-dipropyl-acetamide::CHEMBL99421

SMILES CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)n(C)c2ccccc12

InChI Key InChIKey=WQLGFMXECKHUAW-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50045864   

TargetGastrin/cholecystokinin type B receptor(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045864(2-[2-(4-Chloro-phenyl)-1-methyl-1H-indol-3-yl]-N,N...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]L-365260 from cholecystokinin receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045864(2-[2-(4-Chloro-phenyl)-1-methyl-1H-indol-3-yl]-N,N...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity, measured by displacement [3H]CP-55940 from cannabinoid receptor (CB1) in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50045864(2-[2-(4-Chloro-phenyl)-1-methyl-1H-indol-3-yl]-N,N...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibitory activity by measuring its ability to displace [3H]3-PPP from opiate receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045864(2-[2-(4-Chloro-phenyl)-1-methyl-1H-indol-3-yl]-N,N...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50045864(2-[2-(4-Chloro-phenyl)-1-methyl-1H-indol-3-yl]-N,N...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045864(2-[2-(4-Chloro-phenyl)-1-methyl-1H-indol-3-yl]-N,N...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]ketanserin from serotonin receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50045864(2-[2-(4-Chloro-phenyl)-1-methyl-1H-indol-3-yl]-N,N...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]naxolone binding to opiate receptors in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50045864(2-[2-(4-Chloro-phenyl)-1-methyl-1H-indol-3-yl]-N,N...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045864(2-[2-(4-Chloro-phenyl)-1-methyl-1H-indol-3-yl]-N,N...)
Affinity DataKi:  340nMAssay Description:Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed