BDBM50045875 2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-4-one::CHEMBL99752

SMILES O=C1Cc2c([nH]c3cccc(N1)c23)-c1ccccc1

InChI Key InChIKey=PVFUEKFIIVMPFJ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50045875   

TargetCannabinoid receptor 1(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045875(2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity, measured by displacement [3H]CP-55940 from cannabinoid receptor (CB1) in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045875(2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]L-365260 from cholecystokinin receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50045875(2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045875(2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50045875(2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibitory activity by measuring its ability to displace [3H]3-PPP from opiate receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50045875(2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045875(2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]ketanserin from serotonin receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50045875(2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]naxolone binding to opiate receptors in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed