BDBM50046345 2-{[2-(1-Formyl-4-guanidino-butylcarbamoyl)-pyrrolidine-1-carbonyl]-amino}-3-phenyl-propionic acid::CHEMBL319396

SMILES NC(=N)NCCCC(NC(=O)C1CCCN1C(=O)N[C@H](Cc1ccccc1)C(O)=O)C=O

InChI Key InChIKey=NIMDCAKAZPDUEO-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50046345   

TargetProthrombin(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046345(2-{[2-(1-Formyl-4-guanidino-butylcarbamoyl)-pyrrol...)
Affinity DataEC50:  49nMAssay Description:Inhibitory activity against human thrombin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046345(2-{[2-(1-Formyl-4-guanidino-butylcarbamoyl)-pyrrol...)
Affinity DataEC50:  220nMAssay Description:Inhibitory activity against bovine pancreatic trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046345(2-{[2-(1-Formyl-4-guanidino-butylcarbamoyl)-pyrrol...)
Affinity DataEC50:  2.35E+3nMAssay Description:Inhibitory activity against human plasmin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046345(2-{[2-(1-Formyl-4-guanidino-butylcarbamoyl)-pyrrol...)
Affinity DataEC50:  50nMAssay Description:Inhibitory activity against human thrombin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed