BDBM50046373 CHEMBL108670::{1-(3,4-Dichloro-phenyl)-2-[2-(1-formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)NC(C(=O)N1CCC[C@H]1C(=O)NC(CCCNC(N)=N)C=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=JLNWZEIIEIIPES-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50046373   

TargetSerine protease 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046373({1-(3,4-Dichloro-phenyl)-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046373({1-(3,4-Dichloro-phenyl)-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046373({1-(3,4-Dichloro-phenyl)-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50: 69nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046373({1-(3,4-Dichloro-phenyl)-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046373({1-(3,4-Dichloro-phenyl)-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50: 3.10E+4nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed