BDBM50046425 CHEMBL3314440

SMILES COc1ccc(cc1)-n1nc(C(N)=O)c2CCN(C(=O)c12)c1ccc(cc1)C(C)(C)CO

InChI Key InChIKey=OKARASJFKYWZSK-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50046425   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046425(CHEMBL3314440)
Affinity DataKi:  0.660nMAssay Description:Inhibition of purified human factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046425(CHEMBL3314440)
Affinity DataKi:  2.58E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046425(CHEMBL3314440)
Affinity DataKi: >1.10E+4nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046425(CHEMBL3314440)
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition of human urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046425(CHEMBL3314440)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046425(CHEMBL3314440)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046425(CHEMBL3314440)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human factor 9aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046425(CHEMBL3314440)
Affinity DataKi: >3.76E+4nMAssay Description:Inhibition of human activated protein CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046425(CHEMBL3314440)
Affinity DataKi: >4.30E+4nMAssay Description:Inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed