BDBM50046780 3-Amino-N-[1-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-2-thiophen-2-yl-ethylcarbamoyl]-2-(4-methoxy-phenyl)-ethyl]-3-methyl-butyramide::CHEMBL343555

SMILES COc1ccc(C[C@H](NC(=O)CC(C)(C)N)C(=O)N[C@@H](Cc2cccs2)C(=O)N[C@@H](CC2CCCCC2)[C@@H](O)[C@@H](O)CC(C)C)cc1

InChI Key InChIKey=XIJHLLKKRDODMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046780   

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046780(3-Amino-N-[1-[1-(1-cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 85nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed