BDBM500479 4-(7-fluoroimidazo [1,2-a]pyridin- 3-yl)-7-[[5-(4- hydroxy-1- piperidyl)-2- pyridyl]amino [isoindolin-1-one::US11021481, Compound I-138::US11021481, Compound I-465::US11078201, Compound I-465::US11548890, Compound I-465

SMILES OC1CCN(CC1)c1ccc(Nc2ccc(c3CNC(=O)c23)-c2cnn3cc(F)ccc23)nc1

InChI Key InChIKey=HHGVHLCDLUOZFF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 500479   

LigandPNGBDBM500479(US11021481, Compound I-465 | 4-(7-fluoroimidazo [1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500479(US11021481, Compound I-465 | 4-(7-fluoroimidazo [1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500479(US11021481, Compound I-465 | 4-(7-fluoroimidazo [1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM500479(US11021481, Compound I-465 | 4-(7-fluoroimidazo [1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500479(US11021481, Compound I-465 | 4-(7-fluoroimidazo [1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500479(US11021481, Compound I-465 | 4-(7-fluoroimidazo [1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent