BDBM50048000 5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[1,3,4]thiadiazol-2-ylamine::CHEMBL297733

SMILES Cc1ccc(Cl)c(Nc2ccccc2-c2nnc(N)s2)c1Cl

InChI Key InChIKey=MNFDPAPPAHNLHZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048000   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048000(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50: 690nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048000(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed