BDBM50048271 CHEMBL3315035

SMILES Cn1cc(-c2cccc(Oc3nccc(n3)N3CCOCC3)c2)c2nc3ccccc3cc12

InChI Key InChIKey=TZHRUVMECSOHMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048271   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048271(CHEMBL3315035)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant GST-tagged PDE10A using [3H]-cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048271(CHEMBL3315035)
Affinity DataIC50: 167nMAssay Description:Inhibition of rat recombinant GST-tagged PDE10A using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed