BDBM50048835 CHEMBL3319492

SMILES CC(Nc1cc(F)c(F)c(F)c1)c1cc(cn2c1nc(cc2=O)N1CCOCC1)C(=O)N(C)C

InChI Key InChIKey=DFYAJUKJZQHIIW-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048835   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50048835(CHEMBL3319492)Copy SMILESCopy InChI

Affinity DataIC50: 11nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL