BDBM50048876 CHEMBL52372::[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-(3-phenyl-propyl)-amine

SMILES COc1cccc2C(CCCNCCCc3ccccc3)CCCc12

InChI Key InChIKey=XMJMSAYPJNVDJI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50048876   

Target5-hydroxytryptamine receptor 1A(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50048876([3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50048876([3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-...)
Affinity DataKi:  152nMAssay Description:Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50048876([3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed