BDBM50048878 1-[3-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-propyl]-4-(3,4,5,6-tetrahydro-pyridin-2-yl)-piperazine::CHEMBL300408

SMILES C(CC1CCCc2ccccc12)CN1CCN(CC1)C1=NCCCC1

InChI Key InChIKey=TUSMXFKAPZNQSR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50048878   

Target5-hydroxytryptamine receptor 1A(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50048878(1-[3-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-propyl]-...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50048878(1-[3-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-propyl]-...)
Affinity DataKi:  44nMAssay Description:Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50048878(1-[3-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-propyl]-...)
Affinity DataKi:  111nMAssay Description:Inhibitory activity against Sigma opioid receptor type 1 isolated from whole rat membranes using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed