BDBM50049060 CHEMBL3319502::US10730833, Compound 6'::US9969686, Compound 6'

SMILES C(c1cc2ccccc2[nH]1)c1c[nH]c2ccccc12

InChI Key InChIKey=SHXKYUYEFDONQC-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049060   

TargetAryl hydrocarbon receptor(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049060(CHEMBL3319502 | US9969686, Compound 6' | US1073083...)
Affinity DataEC50:  215nMAssay Description:Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049060(CHEMBL3319502 | US9969686, Compound 6' | US1073083...)
Affinity DataEC50:  215nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetAryl hydrocarbon receptor(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049060(CHEMBL3319502 | US9969686, Compound 6' | US1073083...)
Affinity DataEC50:  215nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent