BDBM50049507 5-Bromo-2-((1S,2R,4R)-2,4-dimethyl-6-methylene-cyclohexylmethyl)-4-methoxy-phenol::CHEMBL50454

SMILES COc1cc(C[C@H]2[C@H](C)C[C@@H](C)CC2=C)c(O)cc1Br

InChI Key InChIKey=XYMDPKIGECPIII-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049507   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049507(5-Bromo-2-((1S,2R,4R)-2,4-dimethyl-6-methylene-cyc...)
Affinity DataIC50: 350nMAssay Description:Antagonistic potency to the human progesterone receptor measured in the T-47D alkaline phosphatase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049507(5-Bromo-2-((1S,2R,4R)-2,4-dimethyl-6-methylene-cyc...)
Affinity DataIC50: 985nMAssay Description:Concentration required to give half-maximal inhibition against human Progesterone receptor B isoform in co-transfected CV-1 cell lines.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049507(5-Bromo-2-((1S,2R,4R)-2,4-dimethyl-6-methylene-cyc...)
Affinity DataKi:  84nMAssay Description:Binding affinity determined for human Progesterone receptor A isoformMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049507(5-Bromo-2-((1S,2R,4R)-2,4-dimethyl-6-methylene-cyc...)
Affinity DataKi:  1.14E+3nMAssay Description:Binding affinity determined against human Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049507(5-Bromo-2-((1S,2R,4R)-2,4-dimethyl-6-methylene-cyc...)
Affinity DataKi:  1.66E+3nMAssay Description:Binding affinity was determined for human glucocorticoid receptor(hGR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed