BDBM50049510 Acetic acid 5-bromo-2-((1S,6R)-4,6-dimethyl-2-methylene-cyclohex-3-enylmethyl)-4-methoxy-phenyl ester::CHEMBL51933

SMILES COc1cc(C[C@H]2[C@H](C)CC(C)=CC2=C)c(OC(C)=O)cc1Br

InChI Key InChIKey=IDYFIJMAKRNLNH-UHFFFAOYSA-N

Data  3 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50049510   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049510(Acetic acid 5-bromo-2-((1S,6R)-4,6-dimethyl-2-meth...)
Affinity DataIC50: 147nMAssay Description:Antagonistic potency to the human progesterone receptor measured in the T-47D alkaline phosphatase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049510(Acetic acid 5-bromo-2-((1S,6R)-4,6-dimethyl-2-meth...)
Affinity DataEC50:  3.01E+3nMAssay Description:Effective concentration against human Progesterone receptor B isoform expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049510(Acetic acid 5-bromo-2-((1S,6R)-4,6-dimethyl-2-meth...)
Affinity DataIC50: 350nMAssay Description:Concentration required to give half-maximal inhibition against human Progesterone receptor B isoform in co-transfected CV-1 cell lines.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049510(Acetic acid 5-bromo-2-((1S,6R)-4,6-dimethyl-2-meth...)
Affinity DataKi:  21nMAssay Description:Binding affinity determined for human Progesterone receptor A isoformMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049510(Acetic acid 5-bromo-2-((1S,6R)-4,6-dimethyl-2-meth...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity determined against human Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049510(Acetic acid 5-bromo-2-((1S,6R)-4,6-dimethyl-2-meth...)
Affinity DataKi:  2.38E+3nMAssay Description:Binding affinity was determined for human glucocorticoid receptor(hGR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed