BDBM50049622 2'-Benzo[1,3]dioxol-5-yl-4',5'-difluoro-biphenyl-4-sulfonic acid amide::CHEMBL300600

SMILES NS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc2OCOc2c1

InChI Key InChIKey=FJQRBWIOLPBVTA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049622   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049622(2'-Benzo[1,3]dioxol-5-yl-4',5'-difluoro-biphenyl-4...)
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049622(2'-Benzo[1,3]dioxol-5-yl-4',5'-difluoro-biphenyl-4...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049622(2'-Benzo[1,3]dioxol-5-yl-4',5'-difluoro-biphenyl-4...)
Affinity DataIC50: 3.98nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed