BDBM50049655 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazine::CHEMBL55189

SMILES CS(=O)(=O)c1ccc(cc1)-c1nccnc1-c1ccc(F)cc1

InChI Key InChIKey=KISKVCPIJSLUGE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049655   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049655(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50049655(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX-2 expressed in Baculovirus infected sf9 cells using arachidonic acid as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50049655(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed